tag:blogger.com,1999:blog-6816519711169456626.post8828778828767282427..comments2023-09-28T03:20:12.066-07:00Comments on The Caregiver Chronicles: Investigational Clinical Amyloid Research in Alzheimer'sBob Tellhttp://www.blogger.com/profile/04328341150299038146noreply@blogger.comBlogger3125tag:blogger.com,1999:blog-6816519711169456626.post-63387270364938639552009-05-09T15:44:00.000-07:002009-05-09T15:44:00.000-07:00Bob you ask some good questions
"Who is sponsoring...Bob you ask some good questions<br />"Who is sponsoring it? Who is paying for it? Whether the investigators are being compensated by a company that stands to profit from the results. In other words, how scientifically "pure" is the research design and control over the ultimate report of the study findings?"<br /><br />The Bapineuzumab trial consists of four arms. Two of which are in the US and two of which are in the rest of the world. The two arms are one for carriers of the APOE4 genotype and the other is for non-carriers. The carrier arm is at a dose of .5 mg/kg and the non-carrier arm has two doses .5 mg/kg and 1.0 mg/kg. They just dropped the 2.0 mg/kg dose in that arm as the result of an interim independent safety review identifying vasogenic edema at that dose. The trials are sponsored by Elan and Wyeth. The trial centers are paid for thier sevices as with any trial. The regulatory agencies in both the US and EU are involved in the trial process and will have the ultimate say in the review of the data, therefore I think you can feel confident that the science is "pure". Just to be 100% above board here I will tell you that I own Elan shares and I came across your post as part of my due diligence of that investment.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6816519711169456626.post-44950539156964172742009-05-04T07:44:00.000-07:002009-05-04T07:44:00.000-07:00Thanks for your encouragement, Mary. I try to stay...Thanks for your encouragement, Mary. I try to stay on top of what is happening in research. One of these days they'll crack the puzzle and Alzheimer's will go the way of polio. It's something to hope for.<br /><br />Bob Tell<br />Author, "Dementia-Diary, A Caregiver's Journal"<br />http://www.dementia-diary.comBob Tellhttps://www.blogger.com/profile/04328341150299038146noreply@blogger.comtag:blogger.com,1999:blog-6816519711169456626.post-71540634617443076162009-05-03T17:35:00.000-07:002009-05-03T17:35:00.000-07:00All good points to ponder, Bob. Thanks for writin...All good points to ponder, Bob. Thanks for writing about this new research.Maryhttp://www.eldercareabcblog.comnoreply@blogger.com